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v1.0.0

🦖 Ancestry Decomposition PCA

by @ClawBio0 pulls
URLopenbooklet.com/s/-ancestry-decomposition-pca
Pinnedopenbooklet.com/s/-ancestry-decomposition-pca@1.0.0
APIGET /api/v1/skills/-ancestry-decomposition-pca

Place your study cohort in global genetic context by computing a joint PCA against the Simons Genome Diversity Project (SGDP) — 345 samples from 164 populations spanning every inhabited continent.

21 skills from this repoClawBio/ClawBio
🦖 Ancestry Decomposition PCAviewing
bio-orchestratorskills/bio-orchestrator/SKILL.md

Meta-agent that routes bioinformatics requests to specialised sub-skills. Handles file type detection, analysis planning, report generation, and reproducibility export.

bioconductor-bridgeskills/bioconductor-bridge/SKILL.md

Bioconductor package discovery, workflow recommendation, setup inspection, and starter code generation grounded in official Bioconductor containers and BiocManager.

claw-semantic-simskills/claw-semantic-sim/SKILL.md

Semantic Similarity Index for disease research literature using PubMedBERT embeddings

ClawBioskills/clinical-trial-finder/SKILL.md
clinpgxskills/clinpgx/SKILL.md

Query the ClinPGx API for pharmacogenomic gene-drug data, clinical annotations, CPIC guidelines, and FDA drug labels

🔍 GWAS Lookupskills/gwas-lookup/SKILL.md

You are **GWAS Lookup**, a specialised ClawBio agent for federated variant queries. Your role is to take a single rsID and query 9 genomic databases in parallel, returning a unified report of GWAS associations, PheWAS results, eQTL data, and fine-mapping credible sets.

💊 PharmGx Reporterskills/pharmgx-reporter/SKILL.md

You are **PharmGx Reporter**, a specialised ClawBio agent for pharmacogenomic analysis. Your role is to generate a personalised drug–gene interaction report from consumer genetic data.

📋 Profile Reportskills/profile-report/SKILL.md

You are **Profile Report**, a specialised ClawBio agent for generating unified personal genomic profile reports. Your role is to read a populated PatientProfile JSON file and synthesize all skill results into a single human-readable markdown document.

📸 Drug Photoskills/drug-photo/SKILL.md

You are **Drug Photo**, a specialised ClawBio agent for medication identification and personalised dosage guidance. Your role is to identify a drug from a photo and generate a genotype-informed dosage card.

🏥 UKB Navigatorskills/ukb-navigator/SKILL.md

You are **UKB Navigator**, a specialised ClawBio agent for searching the UK Biobank data schema. Your role is to take a natural language research question and find the most relevant UK Biobank data fields, categories, and publications using semantic search over embedded schema documentation.

data-extractorskills/data-extractor/SKILL.md

Extract numerical data from scientific figure images using Claude vision + OpenCV calibration. Supports 26+ plot types including bar charts, scatter plots, forest plots, Kaplan-Meier curves, box plots, and more.

diff-visualizerskills/diff-visualizer/SKILL.md

Rich downstream visualisation and reporting for bulk RNA-seq differential expression and scRNA marker/contrast outputs.

equity-scorerskills/equity-scorer/SKILL.md

Compute HEIM diversity and equity metrics from VCF or ancestry data. Generates heterozygosity, FST, PCA plots, and a composite HEIM Equity Score with markdown reports.

galaxy-bridgeskills/galaxy-bridge/SKILL.md

Galaxy tool discovery, intelligent recommendation, and execution — 8,000+ bioinformatics tools from usegalaxy.org with multi-signal scoring and workflow suggestions

genome-compareskills/genome-compare/SKILL.md

Compare your genome to George Church (PGP-1) and estimate ancestry composition via IBS and EM admixture

gwas-prsskills/gwas-prs/SKILL.md

Calculate polygenic risk scores from DTC genetic data using the PGS Catalog

illumina-bridgeskills/illumina-bridge/SKILL.md

Import DRAGEN-exported Illumina result bundles into ClawBio for local tertiary analysis and downstream routing.

labstepskills/labstep/SKILL.md

Interact with the Labstep electronic lab notebook API using labstepPy. Query experiments, protocols, resources, inventory, and other lab entities.

lit-synthesizerskills/lit-synthesizer/SKILL.md

Search PubMed and bioRxiv, summarise papers with LLM, build citation graphs, and generate literature review sections.

methylation-clockskills/methylation-clock/SKILL.md

Compute epigenetic age from DNA methylation arrays using PyAging clocks from GEO accessions or local files.

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